IRCT20130917014693N17
Not yet recruiting
Phase 3
Evaluation the effects of N-acetyl Cysteine supplementation on wound healing and inflammation in patients with diabetic foot ulcer
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Diabetic Foot Ulcer.
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Enrollment
- 100
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients hospitalized in the infectious, internal and orthopedic departments of Loghman Hospital who have type 2 diabetes and unhealed diabetic foot ulcers
- •Patients with grade 3 according to the PEDIS criteria
- •Patients with osteomyelitis involvement proven by MRI or clinical criteria
- •Patients with ankle\-brachial pressure index (ABI) between 0\.9 and 1\.3
- •Patients who have signed the consent form
Exclusion Criteria
- •Patients with a history of taking N\-acetylcysteine, vitamin D and vitamin C in the last 2 weeks
- •Patients with a history of allergy to N\-acetylcysteine ??or its derivatives
- •Patients with a history of asthma and bronchospasm
- •Pregnant and lactating patients
- •Patients taking immunosuppressive drugs
- •Patients who are discharged from the hospital within 1 week
- •Patients who have serum creatinine concentration above 2mg/d
Outcomes
Primary Outcomes
Not specified
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