Evaluation the effects of N-acetyl Cysteine on diabetic foot ulcer

Phase 3

Not yet recruiting

• Conditions: Diabetic Foot Ulcer.; Diabetes mellitus due to underlying condition with foot ulcer; E08.621

• Registration Number: IRCT20130917014693N17
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-07-22

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients hospitalized in the infectious, internal and orthopedic departments of Loghman Hospital who have type 2 diabetes and unhealed diabetic foot ulcers
Patients with grade 3 according to the PEDIS criteria
Patients with osteomyelitis involvement proven by MRI or clinical criteria
Patients with ankle-brachial pressure index (ABI) between 0.9 and 1.3
Patients who have signed the consent form

Exclusion Criteria

Patients with a history of taking N-acetylcysteine, vitamin D and vitamin C in the last 2 weeks
Patients with a history of allergy to N-acetylcysteine ??or its derivatives
Patients with a history of asthma and bronchospasm
Pregnant and lactating patients
Patients taking immunosuppressive drugs
Patients who are discharged from the hospital within 1 week
Patients who have serum creatinine concentration above 2mg/d

Study & Design

• Study Type: interventional
• Study Design: Not specified