Stanford PIPRA Validation Study in an Elderly Orthopedic Population

Completed

• Conditions: Delirium; Postoperative Delirium; Cognitive Impairment

• Registration Number: NCT06567574
• Lead Sponsor: Stanford University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-20
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Inclusion Criteria:<br><br> - Surgical patients<br><br> - Greater than or equal to 65 years old<br><br> - ASA I, II or III<br><br> - Greater than 90 min of surgery<br><br> - Non-cardiac surgery<br><br>Exclusion Criteria:<br><br> - Dementia<br><br> - Alzheimer's<br><br> - Parkinson's<br><br> - Current Benzodiazepine use<br><br> - Alcoholism<br><br> - Previous surgery within the last 12 months or expected in the 12 months to come<br> (except the expected surgery for which they are being enrolled).<br><br> - Color-blindness

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of subjects with postoperative delirium accurately predicted by the PIPRA Tool;Development of post-operative Delirium;Determination of Delirium Phenotype;Impact of delirium on post-operative cognitive impairment;Sensitivity and specificity of the PIPRA tool for detecting postoperative delirium.;Receiver operating characteristic (ROC) curve analysis of PIPRA tool

Secondary Outcome Measures

Name	Time	Method
Immediate Postoperative Mortality;Length of Hospital Length of Stay;Discharge Site;Requirement of Intensive Care Unit Admission;Need of pharmacological protocol