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Clinical Trials/CTRI/2025/09/094227
CTRI/2025/09/094227RecruitingNot Applicable

Assessment of alveolar bone support alterations following Advansync appliance therapy: A CBCT-based analysis.

Krishna Vishwa Vidhyapeeth, School of dental sciences1 site in 1 country20 target enrollmentStarted: September 15, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
20
Locations
1
Primary Endpoint
Evaluation of alveolar bone thickness around mandibular incisors at T0 and T1 phase of therapy.

Study Overview

Brief Summary

The study is conducted to assess the alveolar bone changes seen around mandibular lower incisors on completion with Advansync appliance therapy. A fixed functional appliance is advised for pubertal and post-pubertal patients with skeletal class II malocclusion and a retrusive mandible with a convex profile. The common adverse effect of fixed functional therapy is proclination of lower incisors and which causes changes in alveolar bone thickness around mandibular lower incisors. The balanced occlusion demands that teeth to be placed in the center of the alveolar bone to maintain healthy periodontium and reduce treatment replase tendency. The study will assess the thickness of alveolar bone at the start of treatment (T0) and end of functional therapy treatment (T1) at three different points: crestal, midroot, and apical levels of mandibular incisors.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
13.00 Year(s) to 17.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients having permanent dentition Patients with Class II Division I malocclusion, Convex profile; short mentocervical line; overjet of equal or greater than 5 mm.

Exclusion Criteria

  • Patients with poor oral hygiene.
  • Patients with extreme vertical growth pattern and prior orthodontic treatment Patients on regular antibiotic, steriods and anti-inflammatory drugs.

Outcomes

Primary Outcomes

Evaluation of alveolar bone thickness around mandibular incisors at T0 and T1 phase of therapy.

Time Frame: 5 months

Secondary Outcomes

  • Measurement of buccal, Lingual and total bone thickness at crestal, midroot and apical levels of mandibular incisors at T0 and T1 of therapy.(5 months)

Investigators

Sponsor
Krishna Vishwa Vidhyapeeth, School of dental sciences
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Harshali Zavar

School of Dental Sciences Krishna Institute of Medical Sciences Maharashtra

Study Sites (1)

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