The effect of hydroalcoholic extracts of Nasturtium officinale on antioxidant markers in chronic hemodialysis patients
Phase 3
- Conditions
- Patients with end stage kidney disease under hemodialysis.End stage renal diseaseN18.6
- Registration Number
- IRCT20150622022869N7
- Lead Sponsor
- Yasouj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
Aged over 18 years;
Receive hemodialysis at least twice a week, for about 3 months;
Negative history of using medications with known effect on inflammatory markers such as corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs) in the last month;
No active infectious diseases, malignant, rheumatic diseases and other inflammatory diseases.
Exclusion Criteria
Patients who require additional supplementary therapies (taking medications that affect the inflammatory process during the study)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bun, cholesterol, Low Density Lipoproteinn, High Density lipoProtein, triglyceride, potassium, albumin, calcium and phosphorus and antioxidant tests including malondialdehyde, glutathione peroxidase, superoxide dismutase, high sensitive-CRP, Total Oxidant capacity, Total Antioxidant capacity, P-SH. Timepoint: At the beginning of the study and 28 days later. Method of measurement: Antioxidant and biochemical tests.
- Secondary Outcome Measures
Name Time Method