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Clinical Trials/NCT06394752
NCT06394752
Recruiting
Not Applicable

UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY

Center for Reproductive Health & Gynecology2 sites in 2 countries100 target enrollmentApril 25, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hysteroscopy
Sponsor
Center for Reproductive Health & Gynecology
Enrollment
100
Locations
2
Primary Endpoint
Intrauterine pathology detection rate with Visual Saline Infusion
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This is a prospective, single center, multiple arm cohort study intended to compare the diagnostic accuracy of a Visual Saline Infusion Device (VSI) device, vs standard of care Hydrosonography in reproductive aged women to identify pathology in the uterus.

Detailed Description

This is a prospective, single center, multiple arm cohort study intended to compare the diagnostic accuracy of a Visual Saline Infusion Device (VSI) device, vs standard of care Hydrosonography in reproductive aged women to identify pathology in the uterus. Patients who are enrolled in the study will have a 1) Hydrosonography, and 2) Visual Saline Infusion procedure performed. The Visual Saline Infusion Device is a 2.7mm, steerable tip catheter with a camera and illumination at the distal end. The device is intended to evaluate the intrauterine space in an office based, outpatient setting using minimal volume of fluid (3-5cc's). This study will recruit up to 100 women from a fertility center in Los Angeles.

Registry
clinicaltrials.gov
Start Date
April 25, 2024
End Date
July 30, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Center for Reproductive Health & Gynecology
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients requiring a uterine cavity evaluation
  • Premenopausal women between ages of 18-45

Exclusion Criteria

  • Positive test or history of any of the following conditions:
  • 1a. Chlamydial pelvic infection
  • 1b. Gonorrheal pelvic infection.
  • Positive Pregnancy Test
  • IUD currently in place

Outcomes

Primary Outcomes

Intrauterine pathology detection rate with Visual Saline Infusion

Time Frame: Procedure of approximately 2-5 minute duration

The assessment will involve the examination of the intrauterine cavity for the presence of known pathologies, including polyps, fibroids, adhesions, scar tissue, thickened endometrium, among others. The detection rate will be calculated as the ratio of the number of cases where abnormal pathologies are identified to the total number of cases examined.

Intrauterine pathology detection rate with Hydrosonography

Time Frame: Procedure of 2-5 minute duration

The assessment will involve the examination of the intrauterine cavity for the presence of pathologies, including polyps, fibroids, adhesions, scar tissue, thickened endometrium, among others. The detection rate will be calculated as the ratio of the number of cases where abnormal pathologies are identified to the total number of cases examined.

Secondary Outcomes

  • Visual detection quality score (1-10)(Captured during procedure)
  • Pain during procedure(Collected on day of procedure)
  • Fluid used during distention(Captured during procedure)
  • Adverse events rate(Day of procedure and 24-48 hours post to procedure)

Study Sites (2)

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