Functional and Neurochemical Brain Changes in First-episode Bipolar Mania Following Successful Treatment With Lithium or Quetiapine
Overview
- Phase
- N/A
- Intervention
- lithium
- Conditions
- Bipolar Disorder
- Sponsor
- University of Cincinnati
- Enrollment
- 81
- Locations
- 1
- Primary Endpoint
- The purpose of this study is to use magnetic resonance imaging (MRI) to examine brain structure, function and chemistry in people with bipolar disorder who are being treated with either quetiapine or lithium.
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to use magnetic resonance imaging (MRI) to examine brain structure, function and chemistry in people with bipolar disorder who are being treated with either quetiapine or lithium. Both of these medicines are FDA-approved to treat mania in adults and lithium is also FDA approved in children; quetiapine is commonly used in children with mania, but is not FDA approved for this indication in this age group.
Investigators
Stephen Strakowski
Academic Director of Medicine
University of Cincinnati
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
1
Study subjects receiving lithium
Intervention: lithium
2
Study subjects receiving quetiapine
Intervention: quetiapine
Outcomes
Primary Outcomes
The purpose of this study is to use magnetic resonance imaging (MRI) to examine brain structure, function and chemistry in people with bipolar disorder who are being treated with either quetiapine or lithium.
Time Frame: 8 weeks