EUCTR2020-001765-37-ES
Active, Not Recruiting
Phase 1
Pragmatic clinical trial to evaluate the efficacy of hydroxychloroquine in the treatment of COVID-19 infection in two cohorts: patients with oncohaematological disease and SARS-CoV-2 positive without radiological alteration and sars-cov-2 positive professionals without radiological alteration
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Institut Català d’Oncologia
- Enrollment
- 103
- Status
- Active, Not Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient Cohort
- •1\) Patients diagnosed with onco\-haematological disease
- •2\) Age: over 18 years old.
- •3\) ECOG performance status \< 2 (Karnofsky\>60%)
- •4\) Life expectancy \> 3 months for the neoplastic disease.
- •5\) Patients with laboratory confirmed Covid\-19 diagnosis (PCR)
- •6\) Patients with clinical signs compatible with Covid\-19: fever, cough, dyspnea.
- •7\) Patients should have chest radiological imaging (plaque or CT scan) with no affectation compatible with Covid\-19\.
- •8\) NIT\-1\-2 patients
- •9\) Mild functional alteration of organs, defined as:
Exclusion Criteria
- •Patient cohort and professional cohort
- •? Uncontrolled intercurrent disease including infections other than CoVID19, symptomatic heart failure, unstable angina pectoris, cardiac arrhythmia, psychiatric or social disorder that may limit study requirements
- •? To be receiving any other drug or product under study
- •? Allergy to one or more of the medications in the trial
- •? Chronic concomitant immunosuppressive medication
Outcomes
Primary Outcomes
Not specified
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