Physiopathology and Sequelae of COVID-19 Infection
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 400
- 试验地点
- 2
- 主要终点
- 8-hour cortisol level in patients with Covid19 pneumonia
研究概览
简要总结
The data obtained from Covid-19 infections seem to suggest that the immunogenesis of Covid-19 could in some cases be the result of immune dysregulation. On the other hand, endocrine damage is possible at the tile of Covid-19 infection (mainly thyroid,adrenal, and hypothalamus). These disorders are autoimmune or linked to degeneration.
The main objective is to assess the thyroid function (thyrotropic axis) as well as the corticotropic adrenal function of patients who have had Copvid-19 pneumonia. The secondary objectives is to describe the pathophysiological mechanisms of pulmonary and vasculothrombotic involvement of Covid-19
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient having a covid19 infection hospitalized at the Amiens Picardie University Hospital
- •Patient who is seen in Pneumology consultation for a respiratory assessment at 3 months of his hospitalization (between M2 and M4) to evaluate presence of respiratory sequelae
- •Patient who agreed to participate in the protocol
- •Patient affiliated to a Social Security
排除标准
- •patient under guardianship or curators
- •patient refusing to participate
结局指标
主要结局
8-hour cortisol level in patients with Covid19 pneumonia
时间窗: day 0
8-hour cortisol level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.
TSH level in patients with Covid19 pneumonia
时间窗: day 0
TSH level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.
次要结局
未报告次要终点