Physiopathology and Sequelae of COVID-19 Infection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- Centre Hospitalier Universitaire, Amiens
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- 8-hour cortisol level in patients with Covid19 pneumonia
- Status
- Active, not recruiting
- Last Updated
- 11 months ago
Overview
Brief Summary
The data obtained from Covid-19 infections seem to suggest that the immunogenesis of Covid-19 could in some cases be the result of immune dysregulation. On the other hand, endocrine damage is possible at the tile of Covid-19 infection (mainly thyroid,adrenal, and hypothalamus). These disorders are autoimmune or linked to degeneration.
The main objective is to assess the thyroid function (thyrotropic axis) as well as the corticotropic adrenal function of patients who have had Copvid-19 pneumonia. The secondary objectives is to describe the pathophysiological mechanisms of pulmonary and vasculothrombotic involvement of Covid-19
Investigators
Eligibility Criteria
Inclusion Criteria
- •patient having a covid19 infection hospitalized at the Amiens Picardie University Hospital
- •Patient who is seen in Pneumology consultation for a respiratory assessment at 3 months of his hospitalization (between M2 and M4) to evaluate presence of respiratory sequelae
- •Patient who agreed to participate in the protocol
- •Patient affiliated to a Social Security
Exclusion Criteria
- •patient under guardianship or curators
- •patient refusing to participate
Outcomes
Primary Outcomes
8-hour cortisol level in patients with Covid19 pneumonia
Time Frame: day 0
8-hour cortisol level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.
TSH level in patients with Covid19 pneumonia
Time Frame: day 0
TSH level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.