Isolated Oligohydramnios is Associated With Less Favorable Delivery and Composite Neonatal Outcomes
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Zagazig University
- Enrollment
- 636
- Locations
- 1
- Primary Endpoint
- Delivery mode
Study Overview
Brief Summary
Oligohydramnios happens in 1-5% of term pregnancies. The clinical significance of isolated oligohydramnios been a matter of debate. We aimed in this study to investigate the impact of isolated oligohydramnios on the mode of delivery and risk of adverse perinatal outcome.
Detailed Description
Retrospective study conducted in Armed Forces Hospitals of Southern Region, comparing cases with oligohydramnios (amniotic fluid level index <5) to normal amniotic fluid cases (amniotic fluid level index ≥ 8). Primary outcomes are the mode of delivery and adverse perinatal outcomes (including mortality, NICU admission, low Apgar score and sepsis)
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 50 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Third trimester pregnancy
- •Isolated oligohydramnios
Exclusion Criteria
- •Multiple pregnancy
- •less than 32 weeks
- •medical disorders like DM HPN
- •Fetal jeopardy
Outcomes
Primary Outcomes
Delivery mode
Time Frame: through study completion, an average of 1 year
Either vaginal delivery or cesarean section
Composite neonatal outcomes
Time Frame: through study completion, an average of 1 year
Risk of low Apgar score, transient tachypnea of newborn, ICU admission, etc
Secondary Outcomes
- Induction of labor rate(through study completion, an average of 1 year)
Investigators
Hytham Atia
Associate professor
Zagazig University