Airway Management During Unusual Tracheal Stenosis

Not Applicable

Completed

• Conditions: Tracheal Stenosis
• Interventions: Other: Flow Controlled Ventilation

• Registration Number: NCT05317923
• Lead Sponsor: Istanbul University

Brief Summary

Tracheal stenosis is a serious complication following prolonged intubation. There are important differences in the challenges of airway management. This study consists of our anesthesia management experience in patients with unusual placement of tracheal stenosis due to Covid-19 undergoing tracheal dilatation.

Detailed Description

Tracheal stenosis is a serious complication following prolonged intubation. Two types of tracheal stenosis; Glottic and subglottic stenoses have common features in that they are challenging in terms of ventilation, oxygenation and intubation. However, there are important differences in the challenges of airway managementA thinner tube may be sufficient to overcome the airway difficulty in glottic stenoses. However, in subglottic tracheal stenosis, a thinner tube may not be conveyed to the distal of the stenosis. As a result, adequate ventilation and oxygenation may not be provided with an intubation tube placed proximal to the trachea. This study consists of our anesthesia management experience in patients with unusual placement of tracheal stenosis due to Covid-19 undergoing tracheal dilatation.

Study Timeline

• Study Start: 2022-03-14
• Study First Submitted: 2022-03-14
• Study First Submitted QC: 2022-03-31
• Study First Posted: 2022-04-08
• Primary Completion: 2022-06-30
• Status Verified: 2022-09
• Study Completion: 2022-09-01
• Last Update Submitted: 2022-09-15
• Last Update Posted: 2022-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• ASA 1-2-3 patients over the age of 18 who are scheduled for an elective laryngeal procedure due to subglottic stenosis will be included in our study.

Exclusion Criteria

1. Patients who did not agree to participate in the study.
2. Congestive heart failure (ejection fraction ≤ 35 %)
3. Emergency laryngeal procedures.
4. Patients under 18 years old.
5. Patients with ASA > 3.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
airway management and ventilation in patients with unusual placement of tracheal stenosis	Flow Controlled Ventilation	Flow-controlled ventilation (FCV) in patients with unusual placement of tracheal stenosis

Primary Outcome Measures

Name	Time	Method
PCO2	PCO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion	blood partial pressure of carbondioxide
PO2	PO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion	blood partial pressure of oxygen

Secondary Outcome Measures

Name	Time	Method
length of intubation due to Covid-19 Pnomonia	postoperative period (up to 1 year)	time from intubation to extubation in ICU
EtCO2	EtCO2 value at baseline just before entubation, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion	end-tidal carbondioxide measurement
Myers-Cotton grading scale (1/2/3)	before the surgery	The grade of tracheal stenosis
sPO2	SPO2 value at baseline, peroperative 5, 15, 30, 45 minutes after induction, and before the extubation through surgery completion	peripheral oxygen saturation
VAS (Visual Analogue Scale) score (between 0 to 10 points)	during surgery through surgery completion	surgeons' satisfaction(VAS 0=the worst view, 10= the best view)

Trial Locations

Locations (1)

Istanbul University, Department of Anesthesiology; 🇹🇷 Istanbul, Turkey