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Clinical Trial of Sipjeondaebo-tang on Fatigue of Breast Cancer Patients

Not Applicable
Conditions
Breast Carcinoma
Interventions
Drug: Sipjeondaebo-tang
Registration Number
NCT02858856
Lead Sponsor
Kyunghee University Medical Center
Brief Summary

This is a pilot study that investigate efficacy and safety of Sipjeondaebo-tang on fatigue of patients with breast carcinoma receiving chemotherapy.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
48
Inclusion Criteria
  • men and women aged over 18 years
  • patients who have histologically or cytologically confirmed breast tumor
  • patients who applicable AC(doxorubicin + cyclophosphamide)
  • ECOG score 0 to 2
Exclusion Criteria
  • patient impossible to orally intake
  • patient with dementia, delirium and depression
  • patient suffering from diseases like chronic hepatitis B, C or hepatocirrhosis
  • severe liver disability (3-fold the normal high range value for ALT, AST)
  • patient who has diabetes not controlled by diet, hypertension, hyperthyroidism,
  • severe systemic disease
  • use of other investigational products within the past 30 days
  • hypersensitivity to investigational product
  • others who are judged not to be appropriate to study

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
A groupSipjeondaebo-tangTake Sipjeondaebo-tang on 0\~2 week, 3\~5 week of clinical trial period, total of 4 weeks
B groupSipjeondaebo-tangTake Sipjeondaebo-tang on 6\~8 week, 9\~11 week of clinical trial period, total of 4 weeks
Primary Outcome Measures
NameTimeMethod
Brief Fatigue Inventory change6-11 week
Secondary Outcome Measures
NameTimeMethod
EORTC-QLQ-C30 change0-5 week, 6-11 week
EORTC-QLQ-BR23 change0-5 week, 6-11 week

Trial Locations

Locations (1)

International St. Mary's Hospital

🇰🇷

Incheon, Korea, Republic of

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