Epileptogenic Focus Localization for Children With Epilepsy Using 18F-FDG PET Molecular Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 234
- 试验地点
- 1
- 主要终点
- Accuracy
研究概览
简要总结
This retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with epilepsy.
详细描述
This retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with intractable epilepsy.
Pediatric patients with intractable epilepsy would be retrospectively included in this study. The inclusion criteria included (1) age between 6 and 18 y; (2) detailed seizure semiology evaluation, MRI, EEG and interictal 18F-FDG PET/CT examination; (3) clinical diagnosis as focal epilepsy. The exclusion criteria included (a) any history of central nervous system disease; (b) poor image quality due to head movement.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age between 6 and 18 years.
- •detailed presurgical evaluation, including seizure semiology evaluation, MRI, EEG and interictal 18F-FDG PET/Computer Tomography (CT) examination.
- •clinical diagnosis as focal epilepsy.
排除标准
- •any history of central nervous system (CNS) disease such as trauma and CNS tumor.
- •poor image quality due to head movement.
结局指标
主要结局
Accuracy
时间窗: Through study completion, about 6 months
The accuracy of epilepsy focus localization.
Kappa
时间窗: Through study completion, about 6 months
The agreement between experiment result and clinical diagnosis.
次要结局
未报告次要终点