Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- Subjective Appeal Rating Questionnaire
研究概览
简要总结
This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco product use; and (2) facilitate adult smokers switching to e-cigarettes. There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile. For this substudy, adult smokers (N=200) will attend two laboratory session in which they will self-administer e-cigarette products varied according to within-subject e-cigarette factors (e.g., flavor, nicotine formulation) and smoke their own cigarettes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Regular use of cigarettes containing nicotine.
排除标准
- •Pregnant or planning to become pregnant.
研究组 & 干预措施
E-cigarette e-liquid 1
Participants will self-administer an e-cigarette e-liquid.
干预措施: E-cigarette e-liquid self-administration (Other)
E-cigarette e-liquid 2
Participants will self-administer an e-cigarette e-liquid.
干预措施: E-cigarette e-liquid self-administration (Other)
E-cigarette e-liquid 3
Participants will self-administer an e-cigarette e-liquid.
干预措施: E-cigarette e-liquid self-administration (Other)
E-cigarette e-liquid 4
Participants will self-administer an e-cigarette e-liquid.
干预措施: E-cigarette e-liquid self-administration (Other)
No e-liquid
Participants do not receive an e-cigarette e-liquid to self-administer.
结局指标
主要结局
Subjective Appeal Rating Questionnaire
时间窗: 1 hour
This self-report measure of product appeal will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the appeal rating, with lower scores representing lower levels of appeal and higher scores representing higher levels of appeal.
Smoking Delay Task
时间窗: 1 hour
Minutes delayed before purchasing time to smoke own cigarettes. Scores can range from 0mins to 50mins for the smoking delay task, with lower scores representing fewer minutes delayed from smoking and higher scores representing longer minutes delayed from smoking.
Sensory Attributes Rating Questionnaire
时间窗: 1 hour
This self-report measure of product sensory attributes will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the sensory attribute rating, with lower scores representing lower levels of liking the sensory attribute and higher scores representing greater liking of the sensory attribute.
次要结局
未报告次要终点
研究者
Adam Leventhal
Professor, Department of Preventive Medicine
University of Southern California