Brain Stimulation for Mental Control
- Conditions
- Prevention of PTSD, anxiety, impulsive aggression
- Registration Number
- NL-OMON26132
- Lead Sponsor
- MC Utrecht - Divisie Hersenen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 62
18-60 years of age
-Uncorrected normal hearing
-Provide written informed consent
-Alcohol or drug dependence
-Use of illicit drugs or psychoactive medication within the past two weeks
-Having a current psychiatric diagnosis
-Having a current or previous neurological disorder, e.g., epilepsy, Parkinson’s disease.
-Serious head trauma or brain surgery (N.B. TBI without brain damage or skull damage is no reason for exclusion)
-Large or ferromagnetic metal parts in the head (except for a dental wire)
-Implanted cardiac pacemaker or neurostimulator
-Pregnancy
-Concurrent or recent (within previous month) participation in a neuromodulation or neurostimulation (e.g., tDCS, TMS) experiment.
-Skin damage or diseases at intended electrode sites (tDCS)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reactions to threat of shock in the Neutral, Predictable, Unpredictable Threat test (eye-blink startle, subjective fear ratings)
- Secondary Outcome Measures
Name Time Method - Working memory (N-back task) performance in a threat context;<br>- Inhibitory control (Go/NoGo task) performance in a threat context;<br>- EEG resting-state activity and event-related potentials during above mentioned task performance.