Spinal anaesthesia with bupivacaine with and without magnesium sulphate in patient undergoing uterus surgeries

Phase 1

Not yet recruiting

• Conditions: Inflammatory diseases of female pelvic organs,

• Registration Number: CTRI/2020/02/023169
• Lead Sponsor: Aishwarya Guru

Brief Summary

This is aprospective randomised controlled trial to compare the plain bupivacaine with and without magnesium sulphate given through epidural catheter for patient undergoing total abdominal hysterectomy,among 60 patients are divided in to 2 groups over a period of 18 months.The primary objective is to compare the duration of analgesia between 2 groups.The secondary objectives are onset of action, intra operative requirement of analgesia,looking for side effects like shivering, pruritis , hypotension intra operatively.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-02
• Last Update Posted: 2022-11-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Patients undergoing total abdominal hysterectomy surgery.
• Patients in the age group 40-60 years.
• ASA I & II female.

Exclusion Criteria

• Patient refusal.
• Allergy to local anesthetics/magnesium sulphate ASA III & ASA IV Coagulation disorders.
• Local site infection.
• Poorly controlled Hypertension.
• Poorly controlled Diabetes mellitus.
• Severe CVS abnormalities Renal or Hepatic failure.
• CVS disorders like heart block,myocardial infraction.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of analgesia of epidural block with plain Bupivacaine and Bupivacaine with Magnesium sulphate in patients undergoing total abdominal hysterectomy	Post operative period

Secondary Outcome Measures

Name	Time	Method
Onset of action	Intra op requirement of analgesia

Trial Locations

Locations (1)

Shri sathya sai medical college and research institute; 🇮🇳 Kancheepuram, TAMIL NADU, India

Shri sathya sai medical college and research institute

🇮🇳Kancheepuram, TAMIL NADU, India

Aishwarya Guru

Principal investigator

9669450181

aishwarya.gurus1994@gmail.com