US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries

Not Applicable

Completed

• Conditions: Pain, Postoperative
• Interventions: Procedure: combined thoracic segmental spinal epidural anesthesia

• Registration Number: NCT05587608
• Lead Sponsor: South Egypt Cancer Institute

Brief Summary

Ultrasound-guided combined thoracic segmental spinal epidural anesthesia in comparison with general anesthesia in upper abdominal and breast surgery.

Detailed Description

The first group (S) will be given ultrasound-guided thoracic segmental spinal anesthesia at the level of T10 interlaminar space, patients will be in sitting position, a combined spinal epidural tray will be used. In this group, SonoSite C60x/5-2 MHz M-Turbo Convex Probe ultrasound Transducer to identify the T10 interlaminar space and after complete sterilization, the investigator will introduce the epidural needle in a Paramedian in plan approach till the epidural space. The spinal needle is then introduced through the epidural needle not more than 0.5 cm beyond the Dura matter. 2cc of heavy Marcaine plus 25 ug fentanyl are injected through the spinal needle. The epidural catheter is then threaded through the Touhy needle after withdrawal of the spinal needle to keep only 4cm up in the epidural space.

Study Timeline

• Study Start: 2022-03-01
• Status Verified: 2022-10
• Primary Completion: 2022-10-14
• Study Completion: 2022-10-14
• Study First Submitted: 2022-10-14
• Study First Submitted QC: 2022-10-17
• Study First Posted: 2022-10-20
• Last Update Submitted: 2022-10-29
• Last Update Posted: 2022-11-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

• All upper abdominal and laparoscopic surgeries
• ASA I-III CLASS
• Age between 18 and 60

Exclusion Criteria

Contraindication of regional ASA More than III Age less than18 or more than 60 Psychological troubles

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ultrasound-guided thoracic segmental spinal group	combined thoracic segmental spinal epidural anesthesia	given ultrasound-guided thoracic segmental spinal heavy Marcaine plus 25 ug fentanyl at the level of T10 interlaminar space.

Primary Outcome Measures

Name	Time	Method
MAP	Change from Baseline Systolic Blood Pressure at one day post operative	mean arterial pressure

Trial Locations

Locations (1)

South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt; 🇪🇬 Assiut, Egypt