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Clinical Trials/NCT02524158
NCT02524158
Completed
Not Applicable

Yoga Therapy to Improve Function Among Veterans With Chronic Low Back Pain

VA Office of Research and Development1 site in 1 country152 target enrollmentApril 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Low Back Pain
Sponsor
VA Office of Research and Development
Enrollment
152
Locations
1
Primary Endpoint
Roland-Morris Disability Questionnaire
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Chronic low back pain (CLBP) is a prevalent condition among VA patients, but many current treatment options have limited effectiveness. In addition to chronic pain, people with chronic low back pain experience increased disability, psychological symptoms such as depression, and reduced health-related quality of life. This randomized controlled study will examine the impact of yoga therapy for improving function and decreasing pain in VA patients with chronic low back pain. Although not every VA patient with chronic low back pain will choose to do yoga, it is an inexpensive treatment modality that is increasingly appealing to many VA patients. If yoga is effective, it could become an additional low-cost option that the VA can offer to better serve Veterans with chronic low back pain.

Registry
clinicaltrials.gov
Start Date
April 2013
End Date
December 31, 2016
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Has a VA primary care provider
  • Diagnosis of chronic low back pain \> 6 months
  • Willing to attend a yoga program or be assigned to delayed treatment with yoga
  • Willing to complete 4 assessments
  • English Literacy
  • Has not begun new pain treatments or medications in the past month
  • Willing to not change pain treatments (e.g., discontinue a treatment; increase medication dose) during the 12-week intervention period unless medically necessary

Exclusion Criteria

  • back surgery within the last 12 months
  • back pain due to specific systemic problem (eg, lupus, scleroderma, fibromyalgia)
  • morbid obesity (BMI \> 40)
  • Significant sciatica or nerve compression \< 3 months or chronic lumbar radicular pain \> 3 months
  • Unstable, serious coexisting medical illness (eg, CHF, cancer, COPD, morbid obesity; dementia)
  • Unstable, serious psychiatric illness (e.g., unmanaged psychosis, active substance dependence)
  • Insufficient data to rule out acute, metastatic disease, (unless primary care physician approves)
  • Attended or practiced yoga \> 1x in the last 12 months
  • Positive Romberg test (with or without sensory neuropathy)

Outcomes

Primary Outcomes

Roland-Morris Disability Questionnaire

Time Frame: baseline to 6-months

The primary outcome is the change in Roland-Morris Disability Questionnaire (RMDQ) score between baseline, 12-weeks, and 6-months. The questionnaire consists of 24 questions that ask about back pain-related functional limitations experienced for a variety of daily activities . Scores can range from 0-24. Higher scores indicate more impairment, and when considering the change from baseline to follow-up assessments, negative scores indicate improvement. The scale has been shown to be reliable and is well validated. It has been used in another yoga RCT, allowing for comparisons.

Secondary Outcomes

  • Change From Baseline in Pain Intensity - Brief Pain Inventory at 6 Months(baseline to 6 months)
  • Change From Baseline - Center for Epidemiologic Studies Short Depression Scale (CES-D 10) at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline in Pain Intensity - Brief Pain Inventory at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - SF12 PCS at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Self-efficacy for Managing Low Back Pain at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Fatigue Severity Scale (FSS) at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - EuroQOL 5D (EQ5D) at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Range of Motion - Flexion at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Pittsburgh Sleep Quality Index (PSQI) at 12 Weeks(baseline to 12 weeks)
  • Attendance/ Home Practice(12 weeks)
  • Change From Baseline - Lower Spine Stabilization - Core Strength at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline Pain Interference - Brief Pain Inventory at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - SF12 MCS at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Brief Anxiety Inventory (BAI) at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Grip Strength at 12 Weeks(baseline to 12 weeks)
  • Change From Baseline - Lower Limb Strength and Balance - Eyes Open at 12 Weeks(baseline to 12 weeks)

Study Sites (1)

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