ITMCTR2000003886
Recruiting
Phase 1
Study on the characteristics of immune cell infiltration and its correlation with prognosis in patients with stage III B - IV lung adenocarcinoma by PET-CT based on the theory of 'protecting field' of traditional Chinese Medicine
Dongfang Hospital of Beijing University of Chinese Medicine0 sitesTBD
Conditionsung cancer
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- ung cancer
- Sponsor
- Dongfang Hospital of Beijing University of Chinese Medicine
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with lung adenocarcinoma confirmed by histopathology and / or cytology;
- •2\. Patients who were classified as stage III B \- IV according to the 7th edition of TNM staging system published by IASLC;
- •3\. According to the NCCN guidelines for non\-small cell lung cancer (NSCLC), the first\-line treatment was carried out according to the recist1\.1 evaluation standard for solid tumors;
- •4\. Patients with at least one cold ablation lesion;
- •5\. EGFR mutation (\-), ALK rearrangement (\-);
- •6\. The patients who refused chemotherapy and radiotherapy in recent 1 month planned to receive systemic therapy (oral Chinese Medicine) \+ local treatment (target lesion biopsy \+ cold ablation);
- •7\. ECOG PS \<\= 2
- •8\. Patients whose expected survival time was more than 3 months;
- •9\. Patients with TCM syndrome conforming to any of the five syndromes of lung cancer;
- •10\. Patients who voluntarily participated in the study and signed informed consent.
Exclusion Criteria
- •1\. Patients with multiple primary tumors;
- •2\. Patients with other conditions not suitable for biopsy and cold ablation;
- •3\. Patients with cold ablation lesions who have received other local minimally invasive treatment, such as radiotherapy, radiofrequency, seed implantation, etc.
Outcomes
Primary Outcomes
Not specified
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