Clinical Observation of CHD Phlegm and Blood-stasis Syndrome Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 13,000
- 试验地点
- 1
- 主要终点
- all cause mortality
研究概览
简要总结
Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis. Based on that, the investigator aims to evaluate the evolutionary process of CHD phlegm-blood stasis syndrome by large samples, multi-centre, cross-section observation combining with longitudinal tracking on-site survey method so as to guide the clinical treatment of CHD.
详细描述
Coronary heart disease (CHD) is a major cause of myocardial infarct (MI) and death induced by atherosclerosis or coronary artery spasm. Despite improvements in interventional and pharmacological therapy for acute MI, the mortality early after AMI remains high. Nowadays, as our life quality develops and dietary structure changes, the morbidity of hyperlipidemia dramatically increased. Based on the Chinese medicine, hyperlipidemia belongs to phlegm and it's the basis of atherosclerosis, blood-stasis is the pathological basis of ischemia. Therefore, the investigator proposes that phlegm and blood-stasis syndrome is the main differentiation on CHD. Based on that, the investigator prospectively and retrospectively explores the evolutionary process of CHD phlegm-blood stasis syndrome by large samples, multi-centre, cross-section observation combining with longitudinal tracking on-site survey method.It will provide evidence and guidance to the future clinical treatment using Chinese medicine.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 35 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy or metabolism syndrome people
- •Clinical diagnosis of CHD stable stage or acute coronary disease or CHD heart failure
排除标准
- •Any inflammation, fever, trauma, burn or operation within 1 week
- •Obstructive pulmonary disease
- •Cerebral vascular disease
- •Severe renal or hepatic dysfunction
- •Malignant neoplasms
- •Hematopoietic system disease
- •Sever mental disease
结局指标
主要结局
all cause mortality
时间窗: 6 months
次要结局
未报告次要终点
研究者
Jingqing Hu
Director of Institute of Basic Theory of Traditional Chinese Medicine
China Academy of Chinese Medical Sciences
