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临床试验/NCT02967718
NCT02967718Unknown不适用

Clinical Observation of CHD Phlegm and Blood-stasis Syndrome Patients

Jingqing Hu1 个研究点 分布在 1 个国家目标入组 13,000 人开始时间: 2016年9月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
13,000
试验地点
1
主要终点
all cause mortality

研究概览

简要总结

Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis. Based on that, the investigator aims to evaluate the evolutionary process of CHD phlegm-blood stasis syndrome by large samples, multi-centre, cross-section observation combining with longitudinal tracking on-site survey method so as to guide the clinical treatment of CHD.

详细描述

Coronary heart disease (CHD) is a major cause of myocardial infarct (MI) and death induced by atherosclerosis or coronary artery spasm. Despite improvements in interventional and pharmacological therapy for acute MI, the mortality early after AMI remains high. Nowadays, as our life quality develops and dietary structure changes, the morbidity of hyperlipidemia dramatically increased. Based on the Chinese medicine, hyperlipidemia belongs to phlegm and it's the basis of atherosclerosis, blood-stasis is the pathological basis of ischemia. Therefore, the investigator proposes that phlegm and blood-stasis syndrome is the main differentiation on CHD. Based on that, the investigator prospectively and retrospectively explores the evolutionary process of CHD phlegm-blood stasis syndrome by large samples, multi-centre, cross-section observation combining with longitudinal tracking on-site survey method.It will provide evidence and guidance to the future clinical treatment using Chinese medicine.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
35 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy or metabolism syndrome people
  • Clinical diagnosis of CHD stable stage or acute coronary disease or CHD heart failure

排除标准

  • Any inflammation, fever, trauma, burn or operation within 1 week
  • Obstructive pulmonary disease
  • Cerebral vascular disease
  • Severe renal or hepatic dysfunction
  • Malignant neoplasms
  • Hematopoietic system disease
  • Sever mental disease

结局指标

主要结局

all cause mortality

时间窗: 6 months

次要结局

未报告次要终点

研究者

发起方
Jingqing Hu
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Jingqing Hu

Director of Institute of Basic Theory of Traditional Chinese Medicine

China Academy of Chinese Medical Sciences

研究点 (1)

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