The effect of probiotics on immune cells in patients with pneumonia
- Conditions
- Diseases of th respiratory system
- Registration Number
- KCT0005411
- Lead Sponsor
- The Forces Medical Command
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 80
The diagnosis of pneumonia was based on the ATS/IDSA
guidelines for community-acquired pneumonia. Patient admitted for more than 48
hours, with no alternative foci of infection identified, plus at least, two of
the following criteria - Fever (38?) - Leukocytosis (>12,000/µl) or
leukopenia (<4,000/µl) - Purulent respiratory secretions - Rale (or crackle)
on physical examination - Abnormal blood gas analysis result Plus, new
infiltrates on chest x-ray
- HIV infection, syphylis, diabetes, hypertension, steroid
user - Persons with other serious accompanying diseases when judged by the
researcher.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, <br>constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, <br>albumin, creatinine, Bristol stool scale;clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, <br>constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, <br>albumin, creatinine, Bristol stool scale
- Secondary Outcome Measures
Name Time Method Distribution of immune cells (regulatory T cells, Th17 <br>cells);Distribution of immune cells (regulatory T cells, Th17 <br>cells)