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The effect of probiotics on immune cells in patients with pneumonia

Not Applicable
Completed
Conditions
Diseases of th respiratory system
Registration Number
KCT0005411
Lead Sponsor
The Forces Medical Command
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
80
Inclusion Criteria

The diagnosis of pneumonia was based on the ATS/IDSA
guidelines for community-acquired pneumonia. Patient admitted for more than 48
hours, with no alternative foci of infection identified, plus at least, two of
the following criteria - Fever (38?) - Leukocytosis (>12,000/µl) or
leukopenia (<4,000/µl) - Purulent respiratory secretions - Rale (or crackle)
on physical examination - Abnormal blood gas analysis result Plus, new
infiltrates on chest x-ray

Exclusion Criteria

- HIV infection, syphylis, diabetes, hypertension, steroid
user - Persons with other serious accompanying diseases when judged by the
researcher.

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, <br>constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, <br>albumin, creatinine, Bristol stool scale;clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, <br>constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, <br>albumin, creatinine, Bristol stool scale
Secondary Outcome Measures
NameTimeMethod
Distribution of immune cells (regulatory T cells, Th17 <br>cells);Distribution of immune cells (regulatory T cells, Th17 <br>cells)
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