CBCR for Executive Functions in Patients With ABI in the Chronic Phase
- Conditions
- Acquired Brain InjuryExecutive DysfunctionCognitive Symptom
- Interventions
- Behavioral: Computer based cognitive rehabilitationOther: Sham computerized gaming
- Registration Number
- NCT03558308
- Lead Sponsor
- Katrine Sværke
- Brief Summary
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
- Detailed Description
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury using two clinically developed programmes and one sham-intervention. Furthermore, the study consists of Groups that receives the computerized training both with and witouth support from a professional.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 72
- Persons who are able to give an informed consent both verbally and in writing
- Persons in the chronic phase after stroke or traumatic brain injury (more than one year post onset)
- Persons who score less than the 30. Percentile in one or more of the primary outcome measures outlined above.
- Persons with neurodegenerative diseases
- Persons with diseases which can influence executive functions such as ADHD
- Persons who are motorically or cognitively unable to use a tablet and complete the CBCR-training
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Brain+ with clinical support Computer based cognitive rehabilitation Intervention: Computer based cognitive rehabilitation. This group will train with the programme 'Brain+' and receive continuous support from a clinician during the intervention period. Brain+ without support Computer based cognitive rehabilitation Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Brain+' but receive no support during the intervention period. Cogmed with continuous support Computer based cognitive rehabilitation Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Cogmed' and receive continuous support from a clinician during the intervention period. Sham-training group Sham computerized gaming Intervention: Sham computerized gaming. This group will train computerized solitaire and other computerized games which are thought to be generally cognitive stimulating but with a very limit load on executive functions. This group will receive continuous support during the intervention period.
- Primary Outcome Measures
Name Time Method Trail making test A+B 5 minutes Trail test A: Test of visual attention, trail test B: Test of visual working memory and cognitive shifts
PASAT 3 seconds Paced auditory serial addition test, test of verbal working memory
- Secondary Outcome Measures
Name Time Method Word fluency test 1 min Test of verbal fluency
Digit span (WAIS-IV) 5 minutes Test of verbal memory (forward) and working memory (backward)
Stroop colour and word test 3 minutes Test of inhibition
Quality of Life after Brain Injury (QOLIBRI) 10 minutes Questionnaire about quality of life
Spatial span (WMS-III) 5 minutes Test of visuospatial memory (forward) and visuospatial working memory (backward)
BNI-FS 10 minutes Barrow Neurological Institute Fatigue Scale: Test of fatigue after brain injury
Wordlist, Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) 10 minutes Verbal memory test
SDMT 90 seconds Symbol digit modalities test: Test of processing speed
Trial Locations
- Locations (1)
Center for Hjerneskade
🇩🇰Amager, København, Denmark