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Clinical Trials/NCT05313464
NCT05313464
Enrolling By Invitation
Not Applicable

Effect of Parental Enteral Nutrition on Quality Of Parent-Child Interactions: Prospective Randomized Monocentric Study (PREMIAM)

Centre Hospitalier Intercommunal Creteil1 site in 1 country42 target enrollmentApril 15, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Premature
Sponsor
Centre Hospitalier Intercommunal Creteil
Enrollment
42
Locations
1
Primary Endpoint
behavioural interactions (visual, vocal, mimic)
Status
Enrolling By Invitation
Last Updated
8 months ago

Overview

Brief Summary

Studies underline both the importance of the link and contact that occurs in the earliest days of life and the need to involve parents early with their premature child.

However, the impact of parental nutrition on the later active nutrition and on the quality of parent-child interactions is currently unknown.

PREMIAM study investigates whether active parental participation in enteral nutrition improves the interactions between the infant and his parents, making them more sensitive to their baby's signals and promoting their relational adjustment.

Detailed Description

The importance of parental participation in the feeding of preterm infants has been highlighted by Gianni. In his study of 81 preterm infants in the tertiary centre , the early parental bottle feeding and the skin-to-skin contact were factors promoting withdrawal from enteral nutrition. Moreover, actively participate in care even complex, is desired by parents. Recently, a study compared 10 parent-child dyads and showed that enteral nutrition pushed by a parent (parental nutrition, NP) in comparison of the electric syringe pump , allowed a better perception of the tube by the parents and gave them a sense of utility. The same team randomized 17 preterm infants, born after 28 WA( week amenorrhoea), to receive or not à parent-pushed enteral nutrition The child's behavior changes during nutrition were analyzed in both arms, after scoring of the videos feeding according to the NICAP® ( individualized neonatal assessment and developmental care program) method. Signs of well-being and relaxation of members were more present in case of parental involvement in the delivery of nutrition. These preliminary studies suggest that parental nutrition is well tolerated and improves the comfort of the child and parent during nutrition. However, the impact of parental nutrition on the subsequent active nutrition and on the quality of parent-child interactions is currently unknown.

Registry
clinicaltrials.gov
Start Date
April 15, 2022
End Date
December 28, 2027
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Children born before 30 SA Age of child at start of study: 32 SA

Exclusion Criteria

  • Child with ongoing infection, neurological pathology More than one desaturation and/or bradycardia per hour within 12 last hours Balloon ventilation in last 12 hours
  • Medical contraindication to oral nutrition
  • Intubated child
  • Parents with a disabling mental illness
  • Parents not available
  • Minor parents
  • Parents under guardianship or protection of justice
  • Refusal to sign consent
  • Parents not affiliated with a social security system

Outcomes

Primary Outcomes

behavioural interactions (visual, vocal, mimic)

Time Frame: 34 (W) weeks of gestational age

interactions during the first 10 minutes of an interactive sequence of a premature in the arms of his parent, filmed and coded with The Observer XT software to 34 WA, starting from 3 behaviors of the premature: vocalization, face look mother" and smile

Secondary Outcomes

  • Mother and Father Self-Question Assessment of Parental Competence: The Cognitive and Parental Behaviour Scale (PACOTIS)(at Month 4)
  • Exit age on return home(through study completion, an average of 41 week of gestation)
  • Duration of breastfeeding in number of days.(from 32 week of gestation to 37 week of gestation)
  • Number of children with infant formula change(between 32 week of gestation and 37 week of gestation)
  • Parental time in hours(at 34 week of gestation and 37 week of gestation, calculated over 7 days)
  • Average duration (minutes) of feeding/feeding(at 37 week of gestation)
  • Evolution of the Z-weight score(32 week of gestation at the exit of the child.)
  • Edinburgh Postpartum Depression Risk Rating Scale (EPDS)(at inclusion, at 32, 34 and 37 weeks of gestation)
  • Parental Stressor Scale: Neonatal Intensive Care Unit (PSS: NICU)(at 32, 34, and 37 weeks of gestation)
  • The Montreal Children's Hospital Feeding Scale [MCH-Feeding Scale](4 months of age corrected)
  • Number of desaturation(every day betwenn 32 and 34 weeks of gestation)
  • Number of vomiting(every day between 32 and 34 weeks of gestation)
  • Number of meals and baths given by parents(from 32 week of gestation to 37 week of gestation)
  • Number bradycardia(every day betwenn 32 and 34 weeks of gestation)
  • Duration of transition from passive to active feeding in number of days(from 32 week of gestation to 37 week of gestation)
  • Number and duration of skin-to-skin sessions in minutes(from inclusion to exit of service ( up to 45 week of gestation))
  • Brunet-Lézine and Neurological Evaluation of Amiel Tison simplified by a psychomotor specialized in the development of premature babies to assess the psychomotor development of infants at(4 months of age corrected.)

Study Sites (1)

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