BLENDING: BLENded care for Depressive symptoms IN General practice: a randomised non-inferiority trial
- Conditions
- depressive disorderdepressive symptoms10027946
- Registration Number
- NL-OMON40697
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 302
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
Adult patients, i.e. aged 18 or over;
Patients presenting to the GP with a depressive disorder or depressive symptoms;
Patients for whom GP considers prescribing an antidepressant.
Patients will excluded if they:
- are unwilling to accept randomization to either a psychological (e-prescription) or care as usual.
- have an anxiety disorder or obsessive compulsive disorder as primary diagnosis
- have current substance abuse (alcohol, drugs)
- receive currently treatment for depression (i.e. medication or e-mental health intervention)
- have an insufficient command of the Dutch language
- have not given an informed consent
- No internet available or grossly insufficient computer skills
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main study parameters/endpoints:<br /><br>Main endpoint is the reduction in depressive symptoms as assessed by the<br /><br>Hamilton Depression Rating Scale-17 (HRSD-17) from baseline to three months<br /><br>after intervention. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints are the reduction on depressive symptoms using the HRSD-17<br /><br>at 12 months, percentage response (50% reduction in symptoms on HRSD-17),<br /><br>remission (HRSD-17 score below 7) at three and twelve months of follow-up,<br /><br>antidepressant use, effect on general health status, functional impairment,<br /><br>treatment satisfaction and cost-effectiveness. </p><br>