Diagnostic Value of 18F-Choline PET/CT in Patients With a Thyroid Nodule With an Indeterminate Cytology: Pilot Study

Centre Francois Baclesse1 site in 1 country107 target enrollmentMay 2016

ConditionsThyroid Gland

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Thyroid Gland
Sponsor: Centre Francois Baclesse
Enrollment: 107
Locations: 1
Primary Endpoint: Sensitivity
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of the study is to investigate the contribution of PET-CT with F18-choline in the diagnosis of thyroid nodule with indeterminate cytology in order to guide the best indication of surgical resection.

Registry

clinicaltrials.gov

Start Date

May 2016

End Date

March 28, 2019

Last Updated

7 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Centre Francois Baclesse

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age ≥ 18 years
•Patient with thyroid nodule ≥15 mm with an indeterminate cytology according to the Bethesda Classification 2008 (vesicular lesion of undetermined significance (Bethesda 3); follicular neoplasm or Hürthle cells (Bethesda 4); lesion suspicious for malignancy (Bethesda 5)), and to be operated on
•Patient affiliated to a social security scheme
•Informed consent and signed

Exclusion Criteria

•Thyroid nodules \<15 mm
•Coalescing nodules preventing proper individualization of targeted nodule;
•Thyroid nodule with non-diagnostic cytology (Bethesda 1), benign cytology (Bethesda 2) or malignant cytology (Bethesda 6)
•Hot thyroid nodule on the thyroid scan
•Major subject to a measure of legal protection or unable to consent
•Pregnant women / nursing
•Refusal to participate