MedPath

Effect of oral health on oral leukoplakia - a clinical trial

Active, not recruiting
Conditions
Oral Leukoplakia
Registration Number
CTRI/2017/03/008108
Brief Summary

This study is a randomized, open label, parallel group, single-centre clinical trail, assessing the effect of improving oral health on clinical regression of oral leukoplakia. The primary outcome measures will be 50% regression of oral leukoplakia size within 6 weeks. The secondary outcome will be up to 100% regression of oral leukoplakia size at 3 - 6 months.

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Any form of Oral Leukoplakia, homogenous/non-homogenous diagnosed by clinical inspection and palpation.
  • Patients with Oral Leukoplakia willing to quit their tobacco habit after habit cessation counselling.
Exclusion Criteria
  • Patients not willing to participate in the study.
  • Patients not willing to quit the tobacco habit.
  • Patients who have undergone procedures required for oral health improvement (e.g., periodontic/endodontic treatment) within last 6 months.
  • Patients who were on medication/ underwent any treatment for Oral Leukoplakia.
  • Patients with Oral Leukoplakia along with malignant and other premalignant conditions.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
50% regression of Oral leukoplakia size after improving oral hygiene6 weeks
Secondary Outcome Measures
NameTimeMethod
Up to 100% regression of Oral leukoplakia size after improving oral hygiene3- 6 months

Trial Locations

Locations (1)

Department of Oral Medicine and Radiology, room number 1, Narayana Dental College

🇮🇳

Nellore, ANDHRA PRADESH, India

Department of Oral Medicine and Radiology, room number 1, Narayana Dental College
🇮🇳Nellore, ANDHRA PRADESH, India
Dr Rakesh Kumar Manne
Principal investigator
9704014747
rmannae@rediffmail.com

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.