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Hypofractionated radiotherapy for low and intermediate-risk prostate cancer using robot-tracking stereotactic radiotherapy -phase I/II clinical trial

Phase 1
Conditions
prostate cancer
Registration Number
JPRN-UMIN000014328
Lead Sponsor
Osaka University Graduate School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
Male
Target Recruitment
75
Inclusion Criteria

Not provided

Exclusion Criteria

1) Active double cancer 2) Uncontrollable DM 3) Impossible to stop anticoagulate drugs 4) Severe brain disease 5) Collagen disease 6) Previous pelvic surgery or radiotherapy 7) Previous TUR-P 8) Severe BPH or dysuria 9) Disagree to implant of metallic marker 10) Hormone therapy > 1 year 11) Castration-resistant prostate cancer 12) PSA >20 13) Physician-rated contraindication

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ratio of 2-year late adverse events (genitourinary and gaastrointestinal Grade 2 or more)
Secondary Outcome Measures
NameTimeMethod
2-year biochemical control rate, QOL questionnaire (EPIC + SF-8), dosimetry (dose distribution etc. in radiation physics)
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