NL-OMON46058
Completed
Not Applicable
Measuring static and dynamic cerebral autoregulation intraoperatively in volunteers at different steady-state MBP. - Measuring cerebral autoregulation intraoperatively in volunteers.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cerebral autoregulation
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 66
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •ASA\-I or ASA\-II, willing and able to give written informed consent, scheduled for elective, non\-cardiothoracic surgery under general anaesthesia and age 18 years and above.
Exclusion Criteria
- •Patient related
- •\* Unable/ unwilling to participate
- •\* ASA\-III or higher
- •\* Age \< 18 years
- •\* History of: uncontrolled hypertension, diabetes, Parkinson\*s disease, uncontrolled cardiac arrhythmia, Pure autonomic failure (formerly called idiopathic orthostatic hypotension), Multiple system atrophy with autonomic failure (formerly called Shy\-Drager syndrome), Addison\*s disease and hypopituitarism, pheochromocytoma, peripheral autonomic neuropathy (e.g., amyloid neuropathy, idiopathic autonomic neuropathy), known cardiomyopathy, extreme left ventricle hypertrophy or ejection fraction \< 30%, proven or suspected allergy for any of the medication used during induction of anaesthesia, malignant hyperthermia.
- •\* Unability to record transcranial Doppler ultrasound due to anatomical variance (\~5% of population)
- •\* Contra\-indications for intravenous or inhalational anaesthesia.
- •Surgery related
- •\* Day case surgery
- •\* Laparoscopy with CO2 insufflation
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Assessment of dynamic cerebral autoregulation in near-infrared-spectroscopy using short-distance channels: a feasibility study in acute ischemic stroke patientsAcute ischaemic strokeI63.9Cerebral infarction, unspecifiedDRKS00029613niversitätsklinik für Neurologie Oldenburg54
Recruiting
Not Applicable
Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain InjuryTraumatic Brain InjuryBrain InjuriesBrain Injury, VascularNCT04242602University of Texas Southwestern Medical Center30
Recruiting
Not Applicable
Changes in cerebral autoregulation and cerebral perfusion pressure in patients with preeclampsia. A pilotstudy with transcranial Doppler sonography (Rotterdam Brain Function Study in Preeclampsia -II)preeclampsiatoxemia of pregnancy100146231002690810057166NL-OMON32356Erasmus MC, Universitair Medisch Centrum Rotterdam40
Completed
Not Applicable
Dynamic and Static Autoregulation After Brain InjuryAcute Brain InjuriesTBI (Traumatic Brain Injury)Intracranial HemorrhagesNCT01069250Johannes Gutenberg University Mainz16
Completed
Not Applicable
Do abnormalities in the control of brain blood flow account for dizziness on standing or after meals in older people?SyncopeSigns and SymptomsSyncope and collapseISRCTN92525381niversity of East Anglia (UK)120