Machine Learning-based Classification of Symptom Clusters and Online CBT

Not Applicable

Not yet recruiting

• Conditions: Depression and Anxiety Symptom

• Registration Number: NCT06350201
• Lead Sponsor: Wuhan Mental Health Centre

Brief Summary

To breakthrough the bottleneck identified, we will conduct a cross-sectional study to develop a symptom clustering model for depression and anxiety. A wide range of statistical methods as well as machine learning approaches were explored, and a cohesive hierarchical clustering algorithm will be used. After developing the model, a symptom-matched intervention program based on problem solving therapy will be formulated. We are supposed to examine whether its use for personalizing symptom-matched psychological treatment can lead to improved patient outcomes, compared with usual care. This project is expected to provide a new and precise method for the emotion management, which will provide a standardized intervention pathway combining screening with treatment for the management of depression symptom and anxiety symptom. A preciser intervention matched to individual symptoms may provide important insight in improving patient outcome as well as a standardized mood management pathway targeting to the early detection and intervention for community residents.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-04
• Study First Submitted: 2024-04-01
• Study First Submitted QC: 2024-04-01
• Study First Posted: 2024-04-05
• Last Update Submitted: 2024-04-06
• Last Update Posted: 2024-04-09
• Study Start: 2024-05-01
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Meets the criteria of PHQ-9 and or GAD-7 ≥5 at baseline measurements

Exclusion Criteria

• Patients who report the presence of suicidal thoughts in entry 9 of the PHQ-9 on any psychometric measurements, referred to the Wuhan Psychological Hotline Platform; and
• Those who are currently suffering from mental illness or are being treated with antipsychotic drugs;
• Women during pregnancy or within 3 months after delivery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The Patient Health Questionnaire (PHQ-9)	0 4week 8 week 6-month follow-up 12-month follow-up

Secondary Outcome Measures

Name	Time	Method
7-tiem Generalized Anxiety Disorder Scale,GAD-.7	0 4week 8 week 6-month follow-up 12-month follow-up