Glycosaminoglycans During Septic Shock - a Temporal Study

Withdrawn

• Conditions: Septic Shock

• Registration Number: NCT00814112
• Lead Sponsor: Region Skane

Brief Summary

We have previously shown that the plasma level of glycosaminoglycans (GAG) in septic shock patients are elevated compared to controls. The purpose of this study is to investigate the temporal dynamic of the blood level of GAG in ten septic shock patients. In addition, to assess the kinetics of GAG during septic shock we examine the liver function by galactose elimination capacity as well as excreted urinary GAG.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-11
• Study First Submitted: 2008-12-22
• Study First Submitted QC: 2008-12-22
• Study First Posted: 2008-12-23
• Primary Completion: 2010-11
• Study Completion: 2010-11
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-13
• Last Update Posted: 2024-03-15

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• 2 out of 4 SIRS criteria, where the circulatory criteria must be fulfilled
• Clinical sepsis is suspected
• Informed consent from relative
• Study subject must be over 18 years old

Exclusion Criteria

• Pregnancy
• >24h post sepsis diagnosis
• Ongoing oral or intravenous cortisone treatment for more than one month.
• Malignancy with metastasis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Intensive Care Unit, Lund University Hospital; 🇸🇪 Lund, Sweden