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Clinical Trials/NCT01556984
NCT01556984
Completed
Not Applicable

Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Wuhan General Hospital of Guangzhou Military Command1 site in 1 country200 target enrollmentOctober 2012
ConditionsDiabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes
Sponsor
Wuhan General Hospital of Guangzhou Military Command
Enrollment
200
Locations
1
Primary Endpoint
The changes of endothelial function
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
October 2013
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Wuhan General Hospital of Guangzhou Military Command
Responsible Party
Principal Investigator
Principal Investigator

Xiang Guang-da

Director of Wuhan General Hospital

Wuhan General Hospital of Guangzhou Military Command

Eligibility Criteria

Inclusion Criteria

  • Patients with diabetic foot
  • Age 40 to 70 years old

Exclusion Criteria

  • Heart failure
  • Renal failure
  • Acute infection

Outcomes

Primary Outcomes

The changes of endothelial function

Time Frame: 10 months

Study Sites (1)

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