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临床试验/NCT01556984
NCT01556984已完成不适用

Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Wuhan General Hospital of Guangzhou Military Command1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2012年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
200
试验地点
1
主要终点
The changes of endothelial function

研究概览

简要总结

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
40 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with diabetic foot
  • Age 40 to 70 years old

排除标准

  • Heart failure
  • Renal failure
  • Acute infection

结局指标

主要结局

The changes of endothelial function

时间窗: 10 months

次要结局

未报告次要终点

研究者

发起方
Wuhan General Hospital of Guangzhou Military Command
申办方类型
Other
责任方
Principal Investigator
主要研究者

Xiang Guang-da

Director of Wuhan General Hospital

Wuhan General Hospital of Guangzhou Military Command

研究点 (1)

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