Changes of Endothelial Function Before and After DSA in Patients With Diabetes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diabetes
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- The changes of endothelial function
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.
Investigators
Xiang Guang-da
Director of Wuhan General Hospital
Wuhan General Hospital of Guangzhou Military Command
Eligibility Criteria
Inclusion Criteria
- •Patients with diabetic foot
- •Age 40 to 70 years old
Exclusion Criteria
- •Heart failure
- •Renal failure
- •Acute infection
Outcomes
Primary Outcomes
The changes of endothelial function
Time Frame: 10 months