Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Completed

• Conditions: Diabetes
• Interventions: Other: DSA assay

• Registration Number: NCT01556984
• Lead Sponsor: Wuhan General Hospital of Guangzhou Military Command

Brief Summary

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-03-15
• Study First Submitted QC: 2012-03-16
• Study First Posted: 2012-03-19
• Study Start: 2012-10
• Primary Completion: 2013-08
• Study Completion: 2013-10
• Status Verified: 2015-06
• Last Update Submitted: 2015-06-12
• Last Update Posted: 2015-06-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients with diabetic foot
• Age 40 to 70 years old

Exclusion Criteria

• Heart failure
• Renal failure
• Acute infection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
DSA group	DSA assay	-

Primary Outcome Measures

Name	Time	Method
The changes of endothelial function	10 months

Trial Locations

Locations (1)

Wuhan General Hospital; 🇨🇳 Wuhan, Hubei, China