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临床试验/NCT02279680
NCT02279680Unknown不适用

The Associative Memory in Autism Spectrum Disorders Without Intellectual Disability

University Hospital, Caen1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2014年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
40
试验地点
1
主要终点
The associative memory index

研究概览

简要总结

The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity. The hypothesis of abnormal functioning of the fronto-hippocampal network has been evocated but has never been tested. Hence, the present project will include two complementary assessments conducted on a group of adults aged from 18 to 30 with ASD compared to a control group matched in chronological age and intellectual quotient. The first assessment is devoted to the study of associative memory and its EEG correlates and the second focused on the investigation of perceptual strategies related to associative memory using the technique of Eye-tracking. Both behavioral and imaging data would provide new insights on the relationship between perception and memory in ASD.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Adult between 18 and 30 years old
  • •right handed
  • •affiliated to the french national health care system
  • •ASD only for the group of patients

排除标准

  • •mental retardation
  • •schizophrenia
  • •brain injury with lost of consciousness
  • •neurological disease

研究组 & 干预措施

Patients

Other

Adults between 18 and 30 years old right handing Patients with ASD

干预措施: Electroencephalography (Device)

Patients

Other

Adults between 18 and 30 years old right handing Patients with ASD

干预措施: Neuropsychological assesments (Behavioral)

Healthy volunteers

Other

Adults between 18 and 30 years old Right handing Healthy

干预措施: Electroencephalography (Device)

Healthy volunteers

Other

Adults between 18 and 30 years old Right handing Healthy

干预措施: Neuropsychological assesments (Behavioral)

结局指标

主要结局

The associative memory index

时间窗: 2 years

次要结局

  • theta and gamma oscillations during the associative memory task(2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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