Effects of adrenomedullin in biologics-resistant patients with Crohn disease: randomized, double-blind, placebo-controlled phase 2a clinical trial

niversity of Miyazaki0 个研究点目标入组 24 人开始时间: 2018年5月2日最近更新: 2023年10月17日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方
入组人数: 24

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

In this trial, we observed a long-lasting (24 weeks) decrease in CDAI in the adrenomedullin-treated groups. Adrenomedullin might be beneficial for biologic-resistant CD, but further research is needed.

研究设计

研究类型: Interventional

入排标准

年龄范围: >= 18age old 至 <= 75age old（—）
性别: All

入选标准

•Biologics-resistant patients against maintenance therapy of biologics

排除标准

•Non-responder for biologics
•Patients with small intestinal lesion and having risk of ileus
•Patient with fulminant Crohn disease(CD)
•Patient need early operation for CD
•Patient with active infection
•Patient with severe complication(s)
•Patient with malignancy or past history of malignancy
•Pregnant woman

研究者

发起方

niversity of Miyazaki

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