Evaluation of Lung Ultrasonography Findings in Newborns With Respiratory Syncytial Virus Bronchiolitis
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Lung ultrasonography
研究概览
简要总结
Respiratory Syncytial Virus (RSV) is a seasonal, highly contagious pathogen belonging to the Pneumoviridae (genus orthopneumovirus), a family of negative-strand RNA viruses. Lung ultrasonography; Today, it has become frequently used in neonatal intensive care units because it is a diagnostic, useful, harmless, radiation-free, bedside, reproducible and practical method. The primary purpose of the study is to record lung ultrasound findings and score and thus to compare the agreement between lung ultrasonography and clinical score in the diagnosis and follow-up of newborn babies who are followed up in the neonatal intensive care unit due to bronchiolitis caused by RSV and other viral factors, which are frequently encountered.
详细描述
Respiratory Syncytial Virus (RSV) is a type of negative-strand RNA viruses. It is a seasonal, highly contagious pathogen belonging to the family Pneumoviridae (genus orthopneumovirus). RSV is a common cause of respiratory disease throughout life but is associated with significant morbidity and mortality, especially in infants and older adults.
RSV infections account for approximately 60% to 80% of bronchiolitis in infancy and 40% of pediatric pneumonias.
Bronchiolitis is an acute lower respiratory tract infection that affects children under one or two years of age and is the most common cause of hospitalization, according to American Academy of Pediatrics (AAP) guidelines. Diagnostic criteria for bronchiolitis are based on clinical history and examination.
Lung ultrasonography (LUS) was first used in adults in 1995, and in the last decade, lung ultrasound has proven to be a useful diagnostic tool in many pediatric and neonatal diseases, and its application and benefit in the treatment of bronchiolitis has been reported. Since AUS allows bedside assessment of the subpleural lung for density, thus reducing the quantitative ratio of airspace and space, it is reasonable to expect that a combination of clinical and ultrasound parameters may be useful. Studies have shown that qualitative and quantitative lung ultrasound findings suggest a relationship with the severity of bronchiolitis and are useful in the follow-up of patients.
Caiulo et al. They showed that AUS is a valuable tool in the diagnosis of bronchiolitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 30 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All newborns hospitalized with viral lower respiratory tract findings in the neonatal intensive care unit of Kırıkkale University Faculty of Medicine Hospital
- •Patients with study approval
- •Patients who underwent lung ultrasonography were included in the study.
排除标准
- •Newborns who do not lie down due to viral lower respiratory tract infection
- •Patients without study consent
- •Patients for whom lung ultrasonography could not be performed
结局指标
主要结局
Lung ultrasonography
时间窗: 5 months
It is aimed to compare the agreement between lung ultrasonography and clinical score in the diagnosis and follow-up of newborn babies who are followed up in the neonatal intensive care unit due to bronchiolitis caused by frequently encountered RSV and other viral factors.
次要结局
- lung radrology(5 months)
研究者
Sevde Nur Vural
Asistant Doctor
Kırıkkale University