A Pilot Study to Explore the Role of Gut Flora in Myasthenia Gravis
- Conditions
- Myasthenia Gravis, GeneralizedMyasthenia Gravis
- Interventions
- Other: No intervention
- Registration Number
- NCT04224506
- Lead Sponsor
- ProgenaBiome
- Brief Summary
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Detailed Description
The goal of this Research Study is to better understand how the genetic information in subject's microbiome correlates to Myasthenia Gravis.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
-
Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study
a. May be signed by parent or legal guardian in the case of minor or adult unable to provide consent
-
Male or female of all ages.
-
Diagnosis of Myasthenia Gravis by a physician
- Refusal to sign informed consent form
- History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy.
- Postoperative stoma, ostomy, or ileoanal pouch
- Participation in any experimental drug protocol within the past 12 weeks
- Treatment with total parenteral nutrition
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Myasthenia Gravis No intervention Patients who have been diagnosed with Myasthenia Gravis.
- Primary Outcome Measures
Name Time Method Correlation of Microbiome to Disease via Relative Abundance Found in Microbiome Sequencing Three years Relative abundance of bacterial classes within taxonomic phyla and, more broadly, within their domain will be analyzed by sequencing the gut microbiome. These data will then be categorized with Myasthenia Gravis.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
ProgenaBiome
🇺🇸Ventura, California, United States