Ketamine - Dexmedetomidine(Ketodex) Versus Propofol -Midazolam for Sedation in Patients Undergoing Upper Gastrointestinal Endoscopy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 52
- 主要终点
- Comparison between time of sedation between ketamine Dexametomidine and propofol midazolam in sedation of GI endoscopy
研究概览
简要总结
The goal of this clinical trial is to compare time of sedation between two drugs administered to patients undergoing upper gastrointestinal endoscopy Primary outcome : Time of sedation : is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs
Secondary outcome :
- Recovery time :is the time to reach score 2 of modified Ramsay sedation score starting from injecting bolus dose of study drugs .
- Hemodynamics (MAP,HR) & oxygen saturation
- Drug side effects (nausea,vomitting,agitation)
- Endoscopist satisfaction
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient acceptance
- •Adults aged 21-60 years.
- •Both sexes
- •BMI<35 kg/m2
- •ASA physical status :I& II
- •Patients Undergoing Gastrointestinal endoscopy
- •Duration <30mintues
排除标准
- •• Known allergy to any of the study drugs
- •Unstable Cardiovascular disease
- •Moderate to severe respiratory diseases
研究组 & 干预措施
Ketamine dexmetamodine and propofol midazolam
结局指标
主要结局
Comparison between time of sedation between ketamine Dexametomidine and propofol midazolam in sedation of GI endoscopy
时间窗: Baseline
Time of sedation :is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs
Comparison time of sedation between ketamine Dexametomidine and propofol midazolam in sedation of GI endoscopy
时间窗: Baseline
Time of sedation:is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs
Comparison of time of sedation between ketamine Dexametomidine g
时间窗: Basline
• Time of sedation :is the time to reach score 5 of modified Ramsay sedation score starting from injecting bolus dose of study drugs .
次要结局
未报告次要终点