Functional Outcomes of Stay Strong Stay Healthy Program

Not Applicable

Completed

• Conditions: Memory Loss; Aging; Quality of Life; Cardiovascular Diseases
• Interventions: Other: Resistance Exercise

• Registration Number: NCT02677363
• Lead Sponsor: University of Missouri-Columbia

Brief Summary

Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.

Detailed Description

Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.

Study Timeline

• Study Start: 2016-02
• Study First Submitted: 2016-02-02
• Study First Submitted QC: 2016-02-03
• Study First Posted: 2016-02-09
• Primary Completion: 2017-06
• Study Completion: 2017-06
• Status Verified: 2018-04
• Last Update Submitted: 2018-04-02
• Last Update Posted: 2018-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Age 60 or above
• Enrollment in Stay Strong Stay Healthy Program
• Strength training < 2 hours/week for past 3 months

Exclusion Criteria

• Not enrolled in Stay Strong Stay Healthy Program
• Strength training > 2 hours/week for past 3 months
• Donated more than 463 ml of blood in past 8 weeks
• Physician discouraged to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Older adults	Resistance Exercise	Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.

Primary Outcome Measures

Name	Time	Method
Muscle electrical activity	Change in muscle electrical activity in 8 weeks in response to resistance exercise program	Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.

Secondary Outcome Measures

Name	Time	Method
Exert muscle power/strength	Change in muscle power/strength in 8 weeks in response to resistance exercise program	Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise.
Muscle mass loss	Change in muscle mass in 8 weeks in response to resistance exercise program	Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise.
Ability to think or remember	Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program	Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise.

Trial Locations

Locations (1)

University of Missouri-Columbia; 🇺🇸 Columbia, Missouri, United States