To compare effect of Luliconazole cream versus Ciclopirox olamine cream in Tinea infectio
Phase 4
- Conditions
- Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
- Registration Number
- CTRI/2024/03/063613
- Lead Sponsor
- Pradeep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients willing to give informed consent and follow up.
2)Patients of either gender aged between 18-60 years.
2)Patients with mild Tinea corporis or cruris and Positive KOH Test.
Exclusion Criteria
1)Patients with hypersensitivity to study medications.
2)Patients with deep fungal infections.
3)Patients with Tinea unguim, Tinea capitis and Tinea barbae.
4)Psychiatric or emotional disturbance in patients.
5)Diabetic and Immunocompromised patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary effectiveness is assessed based on percentage of patients achieving complete clearance. Complete clearance is defined as achieving both clinical response and mycological cure. <br/ ><br>Clinical response is assessed using investigator global evaluation tool based on signs and symptoms which give score ranging from 1 to 5.Where score 1:Healed(absence of signs and symptoms), <br/ ><br>score 2:markedly improved greater than 50% clinical improvement, score 3:considerable residual lesion(less than 50% clinical improvement),score 4(no change from baseline),score 5 :deterioration from baseline .Clinical response will be defined as having scores 1 or 2 (healed or markedly improved) <br/ ><br>Mycological cure is defined by achievement of negative result on KOH mount at the end of the treatment period. <br/ ><br>Change in Total symptom score. <br/ ><br>Timepoint: 0,2,4 weeks
- Secondary Outcome Measures
Name Time Method Safety is assessed by adverse drug reactions which will be reported in CDSCO form and severity grading will be done.Timepoint: 0,2,4th week