A Capsular Incision and Biochemical Recurrence After Radical Perineal Prostatectomy
- Conditions
- Radical Perineal Prostatectomy
- Registration Number
- NCT00748514
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
To evaluate the impact of capsular incisions on biochemical recurrence (BCR) and the potential risk factors of capsular incisions.
- Detailed Description
The pathological classification of the prostate following radical prostatectomy provides important prognostic information; an accurate pathology report is the cornerstone to cancer treatment and follow-up. In addition to the preoperative serum PSA, Gleason score on pathology specimens, seminal vesicle invasion and lymph node status, and a positive surgical margin with extraprostatic extension (EPE) are significant predictors of clinical and biochemical recurrence. However, the prognostic implication of a capsular incision, a tumor extending to the inked margins without a histologically documented EPE, remains to be defined.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 266
- pathologically proven prostate cancer
- follow-up for at least 6 months
- insufficient biopsy data
- seminal vesicle invasion or lymph node involvement on pathology
- neoadjuvant or adjuvant therapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method biochemical recurrence of prostate cancer upto the final date of study
- Secondary Outcome Measures
Name Time Method risk factors for capsular incisions at surgery
Trial Locations
- Locations (1)
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine
🇰🇷Seoul, Korea, Republic of