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临床试验/CTRI/2025/09/094961
CTRI/2025/09/094961尚未招募不适用

A prospective longitudinal study on perioperative antimicrobial use pattern for elective surgeries in Orthopedics and General Surgery in a tertiary care hospital

IPGMER and SSKM Hospital1 个研究点 分布在 1 个国家目标入组 320 人开始时间: 2025年10月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
320
试验地点
1
主要终点
To assess perioperative antimicrobial prescribing pattern in selected elective surgeries conducted in the departments of General Surgery and Orthopedics

研究概览

简要总结

This is a prospective longitudinal study which aims to assess perioperative antimicrobial prescribing patterns in elective orthopedics and general surgeries at a tertiary hospital in West Bengal. It evaluates adherence to local and national guidelines. It will help to identify the incidence of surgical site infections (SSIs). Despite existing protocols recommending limited prophylactic use, inappropriate and prolonged antimicrobial use remains widespread in India. This leads to antimicrobial resistance and increased duration of hospitalization and healthcare costs. The study will include around 320 adult patients undergoing common elective surgeries of the hospital. This will have data based on their demographics, clinical history, antimicrobial use and possible outcomes. Statistical analysis will further help to identify possible deviations and inform better antimicrobial stewardship practices.

Almost all studies have mentioned that significant deviation has been noted in real world scenario from recommended guidelines. Therefore further research and audit are needed to understand the lacunae. Though inappropriate usage of antimicrobials in peri-operative procedures is a serious matter of concern there is paucity of studies regarding this in India. Therefore we have undertaken this prospective longitudinal study to evaluate the pattern of peri-operative antimicrobial prophylaxis.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Patients scheduled for elective surgeries.
  • Orthopaedics total knee replacement hip replacement arthroplasty.
  • General surgery laparoscopic cholecystectomy hernia repair.

排除标准

  • Any emergency surgeries Any elective surgeries except the listed.

结局指标

主要结局

To assess perioperative antimicrobial prescribing pattern in selected elective surgeries conducted in the departments of General Surgery and Orthopedics

时间窗: Day 0 to Day 14 | from admission to outcome

次要结局

  • To identify deviations (if any) in the antimicrobial usage pattern from local and national guidelines. To estimate frequency of postoperative infections during hospital stay in the study cohort

研究者

发起方
IPGMER and SSKM Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Pratik Basu

IPGMER and SSKM HOSPITAL

研究点 (1)

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