ISRCTN96797814已完成未知
A randomised controlled trial of gonadotropin releasing hormone agonist (gnRHa) for fertility preservation in oncology patients
Ottawa Hospital Research Institute (OHRI) (Canada) - formerly Ottawa Health Research Institute0 个研究点目标入组 30 人开始时间: 2008年1月15日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •Women who are:
- •1. Between ages 18 to 38
- •2. Who will be undergoing gonadotoxic (sterilising) curative/adjuvant chemotherapy for early stage disease; and
- •3. Have provided informed consent
- •All subjects will be enrolled from the Ottawa Hospital Regional Cancer Institute (OHRCC) and the Cancer Center of South Eastern Ontario at Kingston General Hospital (CCSEO).
排除标准
- •1. Have advanced stage disease and/or whose median survival is expected to be less than 6 months
- •2. Have cancer of the ovaries, uterus, or fallopian tubes
- •3. Have clinical or biochemical evidence of diminished ovarian reserve (recent shortening of cycles less than 24 days between menses, age greater than 38, elevated serum follicular stimulating hormone (FSH) greater than 15 IU/L, or low antral follicle count (AFC - number of follicles less than 10 mm on day 2 or 3 of natural menses) on baseline pelvic ultrasound (less than 5) or elevated day 2 or 3 estradiol (greater than 280 pmol/ml)
- •4. Have previously received chemotherapy or abdominal/pelvic radiation or have planned to receive abdomino/pelvic radiation
- •5. Are pregnant
- •6. Have contraindications to intramuscular injections; or
- •7. Have a history of fractures secondary to/or documented osteoporosis
研究者
相似试验
已完成
4 期
Testosterone for gender dysphoria in transgender meDepressionTransgender healthGender dysphoriaSuicideMetabolic and Endocrine - Other endocrine disordersMental Health - DepressionMental Health - SuicideACTRN12621000716864niversity of Melbourne64
招募中
3 期
Testosterone therapy for the treatment of nonalcoholic fatty liver diseaseNonalcoholic fatty liver diseaseACTRN12619000701123Austin Health120
已完成
3 期
A randomised placebo-controlled trial of testosterone undecanoate in obese men as adjuvant therapy for a weight loss programObstructive Sleep Apnea (OSA)Respiratory - Sleep apnoeaDiet and Nutrition - ObesityACTRN12606000404527The Woolcock Institute of Medical Research60
已完成
不适用
ational randomised trial of hormone replacement therapy (HRT) in women with a history of early stage breast cancerBreastCancerISRCTN29941643Individual Sponsor (UK)3,000
已完成
3 期
Randomized controlled study of GnRH antagonist monotherapy and CAB with GnRH agonist plus bicalutamide for patients with metastatic prostate cancer.metastatic prostate cancerJPRN-UMIN000014243Clinical Research Support Center Kyushu200