The study on the efficacy and the mechanism of repetitive transcranial magnetic stimulation (rTMS) for mood disorders - rTMS trial for mood disorders

Tateishi Hiroshi0 sites34 target enrollmentMarch 14, 2019

ConditionsMajor depression, bipolar disorder

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Major depression, bipolar disorder
Sponsor: Tateishi Hiroshi
Enrollment: 34
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

rTMS treatment significantly improved depressive symptom scores and some subscales of cognitive dysfunction. The partial improvement of cognitive function and the decrease of serum IL-1beta showed a significant correlation.

Registry

who.int

Start Date

March 14, 2019

End Date

September 12, 2020

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Tateishi Hiroshi

Eligibility Criteria

Inclusion Criteria

•1\.Patients with major depression or bipolar disorders who were ineffective for the treatment of more than one antidepressants
•2\.Written informed consent

Exclusion Criteria

•Absolute contraindications are patients with metals in the brain, patients with intracardiac catheters, patients with high intracardiac pressure. Relative contraindications are epilepsy patients, patients with a history of intracranial lesions, oral history of drugs that reduce convulsion threshold, sleep deprivation, alcohol dependence, pregnant women, children, patients with severe heart disease. Regarding cerebrospinal fluid examination, patients with high risk such as bleeding tendency, heparin use, anesthesia allergy, cerebral hypertension etc., or patients judged inappropriate by the psychiatrist.