Efficacy of IV Lignocaine Versus IV Nalbuphine for Attenuation of Pressor Response Diring Laryngoscopy and Intubation in Patients Planned for Thyroid Surgery
试验速览
- 阶段
- 早期 1 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Reduce stress response during intubation and hemodynamic stabilty
研究概览
简要总结
Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated side effects like hypertention tachycardia but also helps in heamodynamically stability at induction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •middle age(18_40)
- •Asa 1 and 2
- •Non hypertensive
- •Thyroid patients
- •patient who gives consent
排除标准
- •hypertensive
- •Asa 3 and 4
- •Patient refusal
研究组 & 干预措施
Lignocain
I/V lignocain 1.5mg per kg given to participants in state dose
干预措施: Lignocaine (Drug)
nalbuphine
I/v nalbuphine 0.1mg per kg given to participants in stat dose
干预措施: Lignocaine (Drug)
结局指标
主要结局
Reduce stress response during intubation and hemodynamic stabilty
时间窗: 10 minutes
Assesment of Hemodynamic stability by observing vital signs
Achieve hemodynamic stabilty and smooth intubation
时间窗: 10 minutes
Assesment of hemodynamic stability by clinical examination of vital signs
次要结局
未报告次要终点
研究者
Amna Sarwar
Principle investigator
Sheikh Zayed Medical College