Glucose and Gastrointestinal Hormone Responses of Subjects With Overweight/Obesity After 12-week Hypocaloric Dietary Intervention Supplemented With a Cereal-based Biscuit Enriched With Plant Proteins
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- change in postprandial glucose response
研究概览
简要总结
Biscuits enjoy high popularity in the human diet and can be excellent snack alternatives and potential carriers of ingredients with appetite regulating properties. In the present study, the effects of a wheat biscuit enriched with plant proteins originated from legumes and seeds on gastrointestinal hormone responses of women with overweight/obesity after a hypocaloric dietary intervention will be examined.
详细描述
Women with overweight/obesity will follow a 12-week dietary intervention supplemented with a cereal-based biscuit enriched with plant proteins or a common isocaloric wheat biscuit as a daily snack.
At the beginning and at the end of the dietary intervention postprandial metabolic responses, body weight reduction and subjective appetite ratings will be examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •non-diabetic women with overweight/obesity
- •constant body weight for the last three months before enrollment
- •standard dietary and physical activity habits
排除标准
- •pregnancy
- •lactation
- •chronic medical illness
- •use of nutritional supplements
- •alcohol consumption >2 drinks per day
结局指标
主要结局
change in postprandial glucose response
时间窗: Time points: 0,30,60,91,120,180 min postprandially at week 0 and week 12.
change in glucose iAUC and glucose concentration at certain time points at the end of the dietary intervention compared to the beginning.
次要结局
- change in postprandial appetite regulating hormone responses(Time points: 0,30,60,91,120,180 min postprandially at week 0 and week 12.)
研究者
Amalia Yanni
Principal Investigator
Harokopio University