Patterns of Breast Cancer Management and Prognosis of Breast Cancer in China：a Multicenter, Prospective, Real-world Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Breast Cancer
- Sponsor
- Fengxi Su
- Enrollment
- 20000
- Locations
- 5
- Primary Endpoint
- Breast-conserving surgery rate,
- Status
- Not yet recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
This is a multicenter, prospective, e, real-world cohort survey initiated by researchers to focus on the patterns of breast cancer management and prognosis of breast cancer in China, and to establish the multicenter, prospective breast cancer data platform. A total of 18 sites in Guangdong and Henan have cooperated to build a cooperative network unit. The sites will conduct prospective and standardized records concerning the clinical pathological features, treatment and prognosis of the early breast cancer patients who are treated in their own site each year, registering in the REDCap system.This real-world cohort study aims to provide a representative and reliable survey data of epidemiological characteristics, clinical treatment and prognosis of patients with early breast cancer in China and explore the establishment of a national multi-center breast cancer data platform model.
Investigators
Fengxi Su
PI
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Eligibility Criteria
Inclusion Criteria
- •Patients who are hospitalized and treated in a collaborative network unit
- •Agree to enroll in the study and sign the informed consent form
- •Histological diagnosis of ductal carcinoma in situ or invasive breast cancer
- •Accept the Surgery-based surgical treatment
- •Willing to cooperate with follow-up work
Exclusion Criteria
- •Previously Excisional biopsy (including minimally invasive resection) of the patient's breast
- •Previously received neoadjuvant chemotherapy
- •Imaging or histological evidence of distant metastasis
Outcomes
Primary Outcomes
Breast-conserving surgery rate,
Time Frame: baseline
the proportion between breast-conserving surgery and breast mastectomy surgery baseline
Breast-conserving surgery rate, sentinel lymph node biopsy rate
Time Frame: baseline
the proportion between sentinel lymph node biopsy and axillary lymph node dissection
Secondary Outcomes
- Disease free survival (DFS)(5year)
- Overall survival (OS)(5year)
- Epidemiological distribution of pathological stage of breast cancer(baseline)