Patterns of Breast Cancer Management and Prognosis of Breast Cancer in China:a Multicenter, Prospective, Real-world Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20,000
- 试验地点
- 5
- 主要终点
- Breast-conserving surgery rate,
研究概览
简要总结
This is a multicenter, prospective, e, real-world cohort survey initiated by researchers to focus on the patterns of breast cancer management and prognosis of breast cancer in China, and to establish the multicenter, prospective breast cancer data platform. A total of 18 sites in Guangdong and Henan have cooperated to build a cooperative network unit. The sites will conduct prospective and standardized records concerning the clinical pathological features, treatment and prognosis of the early breast cancer patients who are treated in their own site each year, registering in the REDCap system.This real-world cohort study aims to provide a representative and reliable survey data of epidemiological characteristics, clinical treatment and prognosis of patients with early breast cancer in China and explore the establishment of a national multi-center breast cancer data platform model.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are hospitalized and treated in a collaborative network unit
- •Agree to enroll in the study and sign the informed consent form
- •Histological diagnosis of ductal carcinoma in situ or invasive breast cancer
- •Accept the Surgery-based surgical treatment
- •Willing to cooperate with follow-up work
排除标准
- •Previously Excisional biopsy (including minimally invasive resection) of the patient's breast
- •Previously received neoadjuvant chemotherapy
- •Imaging or histological evidence of distant metastasis
结局指标
主要结局
Breast-conserving surgery rate,
时间窗: baseline
the proportion between breast-conserving surgery and breast mastectomy surgery baseline
Breast-conserving surgery rate, sentinel lymph node biopsy rate
时间窗: baseline
the proportion between sentinel lymph node biopsy and axillary lymph node dissection
次要结局
- Disease free survival (DFS)(5year)
- Overall survival (OS)(5year)
- Epidemiological distribution of pathological stage of breast cancer(baseline)
研究者
Fengxi Su
PI
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
