Risk Stratified Multidisciplinary Ambulatory Management of Malignant Bowel Obstruction (MAMBO) Program for Women With Advanced Gynecological Cancers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 96
- 试验地点
- 1
- 主要终点
- Optimization of multidisciplinary care
研究概览
简要总结
Management of Malignant Bowel Obstruction (MBO) in Patients with Advanced Gynecological Cancers
详细描述
Guidelines for the management of patients with Malignant Bowel Obstruction(MBO) are not available and as such, there remains an urgent need for a collaborative approach to streamline patient care and optimize use of hospital resources. This study will focus on management of MBO in advanced gynecological cancers.If patients with MBO can be effectively managed in an ambulatory setting, this may improve quality and consistency of patient care, and help reduce volume and duration of bed occupancy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Histologically and /or cytologically confirmed gynecological cancer, including ovarian, fallopian tube, endometrial, cervical or primary peritoneal cancer Deemed to be at risk of developing or have a clinical diagnosis of MBO as defined using the following criteria: clinical evidence of bowel obstruction (history/physical/radiological examination; and bowel obstruction beyond the ligament of Treitz.
排除标准
- •There are no specified exclusion criteria for this study
结局指标
主要结局
Optimization of multidisciplinary care
时间窗: 2 years
To optimize the multidisciplinary care management of MBO in patients with advanced gynecological cancer treated at University Health Network (UHN) which include in-patient and ambulatory management algorithm for MBO • Measured by a ratio of days alive and out of hospital compare to days in hospital within the first 60 days after diagnosis of MBO
次要结局
- Improve patient understanding and awareness of MBO(2 years)
- Evaluation of impact of MBO management on patient reported outcomes(2 years)
- To evaluate nutritional status of patients with MBO(2 years)
- Evaluation of clinico-pathological factors(2 years)
- Record changes in the sum and types of gut microbiome from baseline to study end(1.5 years)
- Determine percentage number of patient microbiome sample analyses completed(1.5 years)
- Evaluate cannabis use in patient population(1.5 years)
- Evaluation of treatment outcomes(2 years)
- Evaluation of impact of MBO management on hospital visits(2 years)