A Multicenter, Prospective, Real World Observational Study for Chronic Total Occlusion
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Enrollment
- 4,006
- Locations
- 19
- Primary Endpoint
- Composite event of all cause death, myocardial infarction, stroke or all kinds of repeat revascularization
Study Overview
Brief Summary
This study evaluated the long-term outcome of patients with chronic total occlusion treated with percutaneous coronary intervention, medical treatment or coronary artery bypass grafting.
Detailed Description
This study is connected with Decision-CTO trial(NCT01078051). Randomized subjects and registry group subjects from Decision-CTO trial continue 10 years follow-up on this study.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 19 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with angina or silent ischemia and documented ischemia
- •Patients with De novo chronic coronary occlusion ≥ 3months and reference diameter ≥ 2.5 mm on coronary angiography
- •Age > 18 years
Exclusion Criteria
- •Refuse to participate in this study
Arms & Interventions
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
Intervention: Percutaneous coronary intervention (Procedure)
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
Intervention: Coronary Artery Bypass Grafting (Procedure)
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
Intervention: Medical treatment (Drug)
Outcomes
Primary Outcomes
Composite event of all cause death, myocardial infarction, stroke or all kinds of repeat revascularization
Time Frame: 10 years
Secondary Outcomes
- Event rate of all cause death(10 years)
- Event rate of rehospitalization due to acute coronary syndrome(10 years)
- Event rate of acute myocardial infarction(10 years)
- Event rate of stroke(10 years)
- Event rate of Procedural success(5 days)
- Event rate of repeat revascularization(10 years)
- The rate change of left ventricular ejection fraction(10 years)
- Composite event of death, myocardial, stroke or repeat revascularization(10 years)
Investigators
Seung-Jung Park
Professor,University of Ulsan College of Medicine
Asan Medical Center