Quantitative Renal Uptake Using TC99m DMSA in Hypertensive &/or Diabetic Patients.

Phase 4

• Conditions: Diabetes Mellitus; Hypertension
• Interventions: Diagnostic Test: DMSA scan

• Registration Number: NCT03123237
• Lead Sponsor: Assiut University

Brief Summary

the investigators explore the possible role of DMSA to detect renal affection in diabetic \&/or hypertensive patients by detecting difference in counts using Tc 99m DMSA in control \& diabetic \&/or hypertensive patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07
• Status Verified: 2017-04
• Study First Submitted: 2017-04-15
• Study First Submitted QC: 2017-04-20
• Last Update Submitted: 2017-04-20
• Study First Posted: 2017-04-21
• Last Update Posted: 2017-04-21
• Primary Completion: 2017-10
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

• • Patients with diabetes (type2), weather controlled or not.

  • Patients with essential hypertension.
  • Patients with diabetes & hypertension.
  • Within normal renal function (urea & creatinine).
  • Control cases may be normal individuals (apparently healthy) like donors for renal transplant.

Exclusion Criteria

• • Patients with abnormal renal function.

  • Patients with diseases known to affect kidney function rather diabetes & hypertension e.g. SLE, heart failure or liver cell failure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	DMSA scan	control will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.
Diabetic & Hypertensive	DMSA scan	Diabetic \& Hypertensive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.
Diabetic	DMSA scan	diabetic cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.
Hypertensive	DMSA scan	hypertesive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Primary Outcome Measures

Name	Time	Method
Renal Counts	2-4 hours	Quantitative Tc99m DMSA renal scan using SPECT technique will be used to measure renal function.

Trial Locations

Locations (1)

Assiut university; 🇪🇬 Assiut, Egypt