Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia

Completed

• Conditions: Septicemia

• Registration Number: NCT03943719
• Lead Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Brief Summary

Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-01
• Primary Completion: 2017-12-31
• Study Completion: 2018-08-31
• Status Verified: 2019-05
• Study First Submitted: 2019-05-08
• Study First Submitted QC: 2019-05-08
• Last Update Submitted: 2019-05-08
• Study First Posted: 2019-05-09
• Last Update Posted: 2019-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 139

Inclusion Criteria

• adult intensive care unit patients with positive blood cultures

Exclusion Criteria

• palliative care patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Turn Around Time to optimal treatment of septicemia	From positivity detection of positive blood culture to administration of optimal treatment (up to 48 hours)	Time in minutes

Trial Locations

Locations (1)

Cliniques universitaires St-Luc; 🇧🇪 Brussels, Belgium