Effect of Empagliflozin on left ventricular volumes in type 2 diabetes or prediabetes patients with heart failure with reduced ejection fractio
Phase 3
- Conditions
- Heart failure.Heart failure, unspecifiedI50.9
- Registration Number
- IRCT20211219053450N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 112
Inclusion Criteria
Patients with type 2 diabetes mellitus (HbA1C= 6.5%) or pre-diabetes (HbA1c between 5.7% to 6.4%) and ischemic heart failure with reduced fractional ejection (LVEF = 40%)
over 18 years old
Functional NYHA Class II to IV
Patient consent for participation in research
Exclusion Criteria
Type 1 diabetes; Severe liver failure; eGFR History of diabetic ketoacidosis;
Existence of any malignancy and cancer;
Lack of adherence to the treatment regimen.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eft ventricular volumes. Timepoint: before and 6 months after intervention. Method of measurement: Echocardiographic parameters.
- Secondary Outcome Measures
Name Time Method