Transcutaneous vagal nerve stimulation to improve cognitive control in patients with Parkinson’s disease

• Conditions: G20; Parkinson disease

• Registration Number: DRKS00025548
• Lead Sponsor: niversitätsklinik für Neurologie, Evangelisches Krankenhaus Oldenburg Neurologie, Fakultät für Medizin und Gesundheitswissenschaften, Carl von Ossietzky Universität Oldenburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

Diagnosis Morbus Parkinson

Exclusion Criteria

Dementia (MMST Score <20), diagnosis of other neurological or psychiatric disorders, patients using medication that affect pupillary reflexes, pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy- and Reaction TIme Data of the Go-NoGo-Change task

Secondary Outcome Measures

Name	Time	Method
tVNS modulation effect on mid-frontal theta activity during Go-No-Go-Change task performance; Pupil-dilation and blood pressure difference before and after stimulation